Tag: B cell signaling
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How Remibrutinib May Control Multiple Sclerosis Through BTK Inhibition
Remibrutinib inhibits Bruton’s tyrosine kinase in B cells and myeloid cells, suppressing downstream immune signaling without directly depleting B cells. This mechanism differentiates BTK inhibitors from anti-CD20 therapies and may influence both peripheral inflammation and CNS neuroinflammation in multiple sclerosis.